منابع مشابه
Ssj50111 967..974
Extraction of soil organic matter (SOM) fractions has been a longstanding approach to elucidating the pivotal roles of SOM in soil processes. Several types of extraction procedures are commonly used, and all provide partial information on SOM function. This report and accompanying papers summarize the information regarding SOM functions in real-world issues that has been gained through physical...
متن کاملDmd056713 974..982
Apicidin, a potential oral chemotherapeutic agent, possesses potent anti-histone-deacetylase activity. After oral administration, the total bioavailability of apicidin is known to be low (14.2%– 19.3%). In the present study, we evaluated the factors contributing to the low bioavailability of apicidin by means of quantitative determination of absorption fraction and first-pass metabolism after o...
متن کامل974 Platelet Membrane Glycoproteins
Glycoproteins I Ib / I I Ia form a Ca2+-dependent complex that functions as the fibrinogen receptor on human platelets (1). Several reports have indicated that this fibrinogen receptor is also expressed on the surface of human monocytes (2-4). Of three monoclonal antibodies directed against platelet I Ib/ I I Ia , two were reported to give a positive reaction with monocytes as well (4). Other i...
متن کاملJgp_201711899 969..974
In the 1980s, medical research set its focus more and more on molecular aspects of diseases, and it was not long until an individual mutation in a single protein species was found to cause the complete phenotype of a disease. Unsurprisingly, ion channels were among those culprits. Significant public attention was aroused when mutations in the (then appropriately named) cystic fibrosis transmemb...
متن کاملDmd050583 966..974
Repaglinide is mainly metabolized by cytochrome P450 enzymes CYP2C8 and CYP3A4, and it is also a substrate to a hepatic uptake transporter, organic anion transporting polypeptide (OATP)1B1. The purpose of this study is to predict the dosing time–dependent pharmacokinetic interactions of repaglinide with rifampicin, using mechanistic models. In vitro hepatic transport of repaglinide, characteriz...
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ژورنال
عنوان ژورنال: Papers. Revista de Sociologia
سال: 2012
ISSN: 2013-9004,0210-2862
DOI: 10.5565/rev/papers/v97n4.551